The Effect of Aqueous Extract of Borago officinalis and Uranyl Acetate on lipid profile and in Albino males rabbits exposed to oxidative stress

Abstract

The effect of aqueous extract of Borago Officinalis and uranyl acetate on activity in oxidation — antioxidants system was designed to estimate (MDA , GSH ) as well as its effect on biochemical parameters (Total cholesterol, triglycerides , low and very low high density lipoproteins to cholesterol , Glucose ).

The   study    showed    that    given   uranyl   acetate    produced     a   significant increment    at  level  (p<0.05)   in  each  average   of  the   Glucose   ,  Total   cholesterol striglycerides   , LDL-C,VLDL-C   and  MDA  as  compared   with  control   group. Whereas    there  was  a  significant    decrement    at  level  (p<0.05)   in each  average   of the HDL-C ,GSH as compared  with control  group  . whereas  the treatment  of the albino   males   rabbits   by  uranyl   acetate   and  aqueous   extract   resulted   in  a significant  reduction  at  level (p<0.05) as  compared  with  uranyl  acetate  group only through  the average of the Glucose , Total cholesterol  , triglycerides  , LDL- C,VLDL-C, MDA .Whereas  increment  in average of High Density Lipoprotein  — Cholesterol  and  GSH. The  treatment   of  the  albino  males  rabbits   by  aqueous extract    only   resulted    in  a  significant    increment    at  level  (p<0.05)   as  compared  with  control  group  through   the  average  of  the  Glucose triglycerides  , LDL-C,VLDL-C,  MDA ,  and  resulted  in a significant  decrement through  the average of HDL-C and GSH.