Effects of halothane and isoflurane on QT interval in young patients underwent hemorrhoidectomy

Abstract

Background   Long  QT  syndrome (LQTS) is  a  heart  rhythm  disorder that  can potentially  cause fast, chaotic heart beats. These rapid heartbeats may trigger a sudden fainting  spell or seizure. In some cases, your heart may beat erratically for so long that it can cause sudden death.

The aim of study is to evaluate the effects of halothane and isoflurane  on QT interval in patients underwent  hemorrhoidectomy.

patients   and  methods  ECG were  recorded  in operative  theater  at al-shurgat  general hospital just before  surgical operations  and directly after end of operation    , 37 young , healthy  patients were participated  in this study 29 male and 8 female (n=17)received    halothane (20) received isoflurane.

Results:   The  mean  and  standard  deviation  of  participants   age  and     duration   of ] operation   was   considerably    higher   among    those   who   received    halothane    in | comparison  to isoflurane   and differences was statistically  significant  and the mean of age was 29.35+5.958  years   with halothane  and 24.55+4.893  years  with isoflurane  , | (p-value  0.011)  and regarding  the  mean of duration  of operation    was  19.47 +3.243 minutes with halothane and 16.75+3.240 minutes  with isoflurane use ,(p-value  0.023)  | Conclusions    the   present   study   conclude   that   maintenance    of   anesthesia   with halothane might prolong the QT-interval and did not result  in arrhythmias while  , with isoflurane was not associated ~ with alterations in the QT-interval  and induced no changes in cardiac rhythm