Thyroid Lesions a Clinicopathological Study

Abstract

Over   eleven   months   period   from   October   2003   until September 2004, (200) patients with surgically treated thyroid disease  in  Mosul  city  were  collected.  The  patients  were examined    clinically    ,    and    the    biopsies    examined     histologically. 
         There were 170 females and 30 males and the female to male ratio    was 5.6:1 .The age ranged between 14 and 75 years,  with a mean  of 36.4 years. The peak age incidence was at 3  and 4  decades. Seventy percent of the patients 
rd
the patients  were  urban  and the rest were  rural areas. 
         On clinical examination 57% had multinodular goiter ,11.5%  had diffuse enlargement and 31.5% presented with single nodule. Among the single nodules, 66.6% were right sided, 31.7% left sided, and 1.5% had single nodule in the isthmus. 
         Ultrasound examination was performed on 50 patients and  revealed    26%  cystic  ,66%  solid  ,  and  8%  mixed echogenicity. 
         On histopathological examination there were 52% non toxic  nodular  goiter,  17.5%  toxic  nodular  goiter,  11% thyroiditis,  8%  adenoma,  and  11.5%  thyroid  malignancy. Papillary carcinoma formed 78.2%, of all malignant lesions, follicular carcinoma formed 17.4%, and medullary carcinoma constitute 4.3% of malignant lesions.  
         FNAC was done for 84 patients; 69 of them were benign and  8  were  malignant  with  2  false  positive  and one  false negative.  The  sensitivity,    specificity,  and  accuracy  was; 88.8% , 97.1% , 96.2% , respectively.