Estimation the level of IgE in Asthmatic children

Abstract

Background: This study was done to detect the level of IgE in asthmatic children.                            
Aim: The aim of this study is to evaluate the relation between asthma in children and IgE level in children.     
Study Design: Case-control study. 
Patient study: This study was performed in Mosul city from January 2019 to June 2019. The total number of children in this  study  was  200  (152  patients  and  48  control)  were recruited from the emergency department, outpatients clinics of  Ibn  al-Atheer  teaching  hospital  for  children,  pediatric private clinic and from primary schools of children in Mosul city.  The  sample  size  was  152  patients  with  asthma  (109 males  and  43  females)  whose  age  between  1-15  years.  Methods:  5  ml  of  blood  were  collected  by  vein  puncture using  disposable  syringe  from  each  patients  and  control enrolled in this study for determination of IgE levels using enzyme linked immune-sorbent assay (ELISA technique).  Result:  IgE  levels  was  significantly  elevated  in  asthmatic children and even in some control cases.   
Conclusion:  There  was  a  strong  association  between Asthmatic children and elevated IgE levels in most of patients and some control cases.