Comparism between GeneXpert test and direct sputum smear in diagnosis of tuberculosis in tuberculosis centre in salahaldin Governorate in 2018-2019

Abstract

Tuberculosis  (TB)  is  a  communicable  disease  resulting  from infection with Mycobacterium tuberculosis .Tuberculosis remain  a leading cause of mortality in the world , nearly one third of the global population is infected with Mycobacterium tuberculosis , which is at risk of developing the disease . Iraq is considered to be a middle burden country with tuberculosis The current study was done on (125) patients suffered from symptoms of pulmonary TB, the  information  collected  from  center  records  in  order  to comparison between the results of GeneXpert test and results of direct sputum smear (AFB) for year 2018-2019. 
The males were 63 (50.4%) patient with mean age of them was 40.97±  14.2  years  ,  while  the  females  represented  62  (49.6%) patient with mean age of them was 44.4 ± 17.1  years without significant difference between them . The early morning sputum samples for Ziehl-Neelsen stain were obtained from all patients. Which revealed positive in 7 (11.11%) male patients and 4 (6.45) of female patients. 
Genexpert test for sputum samples was performed in 125 patients which was positive in 23(18.4%) patients as 14(22.22%) males and 9 (14.15%) females. 
The two tests was positive in 11(8.8%) of patients. 
The results of GeneXpert test and direct sputum smear statistically was not significant.