Evaluation of liver enzymes in patients with renal failure

Abstract

Background and Objective: Renal failure is a disorder with a feature of high urea and creatinine level with the outcome of anunexpected decrease in kidney function resulting in a significant decline in glomerular filtration rate. Apart from the major clinicalimportance of ABO blood group on blood transfusion and organ transplantation, there seem to be strong associations betweenblood group types and some diseases as a result of the carbohydrates compound found on the surface of the red blood cellmembrane. This study aims to determine the effect of ABO blood group on renal disease patients. Materials and Methods: This case study was conducted on 150 patients with renal failure attending Dialysis unit in Tikrit Hospital from April-June, 2022. Ethical approval and patient consent statements were taken from everyone  and  the  study  was  performed  in  the  Medical  Laboratory department of the hospital. Total 3 mL of patient blood was put into plain bottles. Serum was used to the determine ABO blood group was done with red cell samples by tube agglutination method. The data obtained were analyzed by SPSS software version 22.  
Results: Generally, the study revealed a strong association of ABO blood group  on  renal  failure  (p<0.001).  However,  Group  O  antigen  was statistically discovered to cause the severity of renal failure (p<0.05). Conclusion: The results showed that blood group O individuals are more susceptible and suffer severely in renal disease than other blood group individuals.