Determination Of Some Oxidative Stress Markers In Sheep Diagnosed With Anemia In Salah Al-Deen Governorate

Abstract

Background: The purpose of this study was to determine the changes of oxidation stress markers in sheep suffering from nutritional deficiency anemia. Additionally, the blood picture of these sheep was examined and compared to that of non-anemic sheep, which served as a control group. Methods: Sheep aged 1-3 years who were clinically classified as anemic and non-anemic according to clinical symptoms were involved in the study. The study included 40 sheep divided to two groups, 30 animals as anemic group, and 10 animals as control group. The percentage of hemoglobin and the amount of red blood cells were also measured to validate this diagnosis. Superoxide dismutase, glutathione, and malondialdehyde were among the oxidation indicators.

Results: The findings demonstrated that the levels of each of the three (Hb, RBC, and HCT) were significantly Lesser (p≤0.05) in the groups of animals identified as anemic, as verified by blood picture tests, when compared to healthy animals. The levels of super-oxide dismutase and glutathione in anemic animals were significantly Lesser (p≤0.05) than in the control group, but the levels of malondialdehyde in anemic animals were significantly upper (p≤0.05) than in the control group.