Assessment of Concentration interleukins and liver function in patients infected with hepatitis type –B

Abstract

Background : Hepatitis B virus (HBV) is one of the global problems that causes liver disease and thus leads to death. In 2019, the World Health Organization indicated that 296 million people worldwide suffer from hepatitis C virus infection. Hepatitis B virus primarily affects liver cells and replicates within them.

Materials and Methods: This study was conducted on patients attending and admitted to Balad General Hospital in Salah al-Din for the period (1/6/2024-25/11/2024), and the groups were classified into two groups, the first group, which included 40 healthy people (control group), and the second group, which included 50 patients infected with viral hepatitis B, and the ages of the samples targeted in the research ranged ( 25-60) years of age, a questionnaire was prepared that included information about age, patient history, blood receipt, and visit to the dentist. blood was then collected from patients and healthy people and separated using a centrifuge. Then immune and liver function variables were measured, which included (IL-2, IL-4, IL-8, AST.ALT.ALP)

Results: The current research showed a significant elevated in each of the levels (IL-2, IL-4, IL-8, AST, ALP, ALT). In the blood sera of patients infected with viral hepatitis B and healthy people, at its level, the probability of P ≤ 0.05.