Serum Thyroid Hormones and Cortisol in Patients with Chronic Renal Failure

Abstract

Background Thyroid hormones are necessary for growth and development of the kidney and for the maintenance of water and electrolyte homeostasis. The effects of hypothyroidism on the kidney are usually opposite to the effects of hyperthyroidism. Patients and Methods: Serum samples were collected from 120 individuals, 50 of these individuals were normal and 70 chronic renal failure (CRF) patients that aged from (18-60) year with no personal history of Hypertensive. Thyroid diseases or Diabetes Mellitus. Serum samples were collected from renal failure patients that admitted to dialysis unit of Tikrit Teaching Hospital from August 2012 to January 2013. The Results :Blood urea, S.Creatinine, S.TSH, S.Cortisol, Potassium and Chloride were increased in CRF. while T3. T4 and Sodium were decreased rather than control. Conclusions: These findings suggest the presence of intrathyroidal and pituitary disturbances associated with uremia.