Relationship hetween estrogen hormone as risk factor and development of breast and endometrial cancer

Abstract

Breast cancer is a complex disease and may be sub-divided into hormone-responsive [estrogen receptor (ER) positive] and non-hormone-responsive  subtypes (ER-negative), and remains a common disease throughout the world and endometrial cancer is the most common gynecological malignancy.
This study aimed to detect the relationship between estrogen hormone as a risk factor and development of breast and endometrial cancer.
Out of(156) cases, only (62) cases ofbreast cancer depended upon data collection ofpatients and (94 ) cases with reports during from first of January to last of march 2014.
The result revealed that at the age (40-49) years was (38.3%), P<0.005 followed by the age (50- 59) years (22%), P<0.005 ,so that the results were significant.
Ductal type of breast cancer recorded (86.8%) while lobular type recorded (13.|%)Left side of breast cancer recorded (56.36%) while right side (43.63%) .Endometrial  cancer was recorded at the age (40-49) years (75Yo) followed by (50-59) years (l2.5oh) P<0.005, so it is significant.
It was concluded that the estrogen status effects on development of breast cancer mainly.