Serum insulin like growth factor-I and Inhihbin B levels in patients with polycystic ovarian syndrome

Abstract

Design: A cross section study the relationship between serum inhibin B level and Insulin Growth Factor I level, and the fertility outcome in Polycystic Ovarian Syndrome women. Setting: The study conduct at Tikrit Teaching Hospital, Department of Obstetrics and Gynecology between May 2010- May 2011.
Patient: Ninety women participate with study they were included in one of the following groups:
Group A: includes fifteen normal fertile women.
Group B: includes fifty infertile Polycystic Ovarian Syndrome women
Group C; includes twenty five fertile Polycystic arian Syndrome women.
Polycystic. ovary syndrome is diagnosed according to the ESHRE/ ASRM Rotterdam criteria for Polycystic Ovarian Syndrome 2004.
Methods: Clinical, anthropometric measurements, ultrasound study and laboratory determinations of Follicular Stimulating Hormone, Prolactin, inhibin B,
Leutanizing Hormone, Insulin like Growth Factor I.

Results: Serum inhibin B decreased in older infertile Polycystic Ovarian Syndrome women than fertile Polycystic Ovarian Syndrome women. Infertile Polycystic Ovarian Syndrome women have higher serum Insulin like Growth Factor I and Inhibin B than fertile PCOS and control group.
Conclusion: Infertile Polycystic Ovarian Syndrome women associated with elevated serum inhibin B and serum Insulin like Growth Factor I levels.