Therapeutic Effect of intravenous Pentaglobulin In Treatment of neonatal sepsis

Abstract

Neonatal   sepsis  is  the  leading   cause  of  morbidity   and  mortality   in  neonates   if developing         countries,  intervention  trials  showed that  using  Pentaglobin   in neonata sepsis decrease morbidity  and mortality.
Patients and Methods:-
The study included  100 patients  sustained neonatal  sepsis, (age 0-30 days), fifty patient were  treated  with  antibiotics  only,  and  the  remaining   50  patients  were  treated  with antibiotics and pentaglobin  as an adjuvant therapy.
Results:-
The study showed that improvement occurred when treatment included (Pentaglobin) i 74% compared to 38% in case of treatment with plain (antibiotics) with a relative risk o 1.95.
Conclusions:-
Pentaglobin  is useful in the management  of neonatal sepsis.
Recommendations:-
Pentaglobin  may  be  added  to the  (antibiotics)  in the  management  of  neonatal  sepsis further studies are required to determine the cost effectiveness.