Estimation of copper & zinc in plasma of acute lympoplastic leukemia

Abstract

Several works have shown that a definite relationship that exists between trace elements & certain diseases. the aim of this study is to investigate the change in plasma copper & zinc of acute lympoplastic leukemia. 41 subjects were participating in this study; 20 healthy subjects & 21 patients suffer from acute lymphoblastic leukemia (ALL). Blood samples were collected & plasma copper & zinc concentrations were measured. Plasma zinc is significantly lower in ALL patients than control by (p<0.01), whereas plasma copper is higher in ALL patients than control by 14.7%. In the present study, p.cu/p.zn ratio of control (19%) was lower than that of ALL patients (24.7%). The higher ratio of patients is due to reciprocal changes of copper & zinc. This index may better than copper or zinc alone.