The pattern of calcium pyrophosphate dihydrate crystals among Iraqi patients in salaheldin area

Abstract

The aim of this study was to show the prevalence of calcium pyrophosphate  dihydrate  crystals  (CPPD)  deposition  among patients clinically diagnosed with acute monoarticular arthritis and to determined the difference between uric acid crystals deposition and  CPPD  deposition  in  joints  among  patients  with  acute monoarticular  arthritis.  This  study  was  carried  out  among  50 patients with monoarticular arthritis includes 36 females and 14 males from salaheldin area ages were ranged between 30-80 years with mean (55 years) attended rehabilitation hospital in Tikrit. All were  reviewed  with  history,  thorough  examination  and investigation. Aspiration of synovial fluid were collected from patients who give informed consent aseptically into sterile plastic tubs and examined by polarised light microscope. Also culturally using standard techniques and tested for micro- organism. Sample were cultured and incubated at 37C°  aerobically for 24 hours. No significant bacteria was shown. But examination under polarised light  microscope  shown  birefringent  test  weak  positive  with rhomboid shape of CPPD crystals which is differ from uric acid crystals which shown negative birefringent test and needle shaped. Also  study  show  2%  of  patient  with  hyperparathyroidism  on treatment, 2% of patients with hemochromatosis.