Correlation Of Prolactin Hormone With The Thyroid Gland Hormones And The Female Sexual Hormones In Infertility Women

Abstract

Background:   infertility is defined as not being able to get pregnant. Hormonal disorders of female reproductive system are comprised of a number of problems resulting from aberrant dysfunction of hypothalamic- pituitary-ovarian axis. These relatively common disorders often lead to infertility.                                                               
Aims: This study aimed to evaluate the concentrations of a group of   hormones, They acted as a marker to make the functional changes in ovaries or caused the infertility or Sub Infertility  in some women . the study involved estimating the concentration of the prolactin ( PRL) , follicle stimulating hormone ( FSH) , luteinizing hormone (LH) , estrogen (E2) and cortisol in addition to assess the concentrations of thyroid stimulating hormone (TSH) , thyroxin (T4) and Triodeothyronin(T3)  as well as find the correlations between  prolactin  hormones and the studied hormones,  the study covered (30) samples of infertility women ranged their age between (28-48) compared with (15) healthy samples treated as a control group .
Result :The results of study showed a significant increase (P<0.05) in concentrations of prolactin  (PRL) , follicle stimulating hormone (FSH) , luteinizing hormone (LH) , cortisol and the thyroid stimulating hormone (TSH) in the patients whereas these results also indicated to a significant decrease (P<0.05) in concentrations of estrogen (E2) , (T4)and (T3) .The results of the correlations showed a positive correlation between prolactin hormone and ( TSH ) at probability level ( p <0.01 ) and with )FSH( (LH), and cortisol at probability level ( p<0.05 ) whereas the correlation was negative between prolactin hormone and estrogen (E2) , (T4) and (T3).