Comparative study to assess the effect of different antibiotics administration and other factors on post cesarean wound infection

Abstract

Wound infection is infection at any level from 1-30days of the operation  or  up  to  one  year  after  operation  if  included  the embedding of foreign body, reasonable use of antibiotic is one of the  key  factor  to  stop  wound  infection  .The  administration  of prophylactic  antibiotic with recommended regimens, such as in developed countries has not been applied in AL-Batool hospital 
.This hospital still used other types of antibiotics, in addition for several  reasons,  antibiotics  were  continued  postoperatively  to reduce the risk of delayed infections. Therefore,  this study  was done to analyze the effectiveness of prophylactic antibiotics as recommended in cesarean  sections , This is a prospective  cohort study  carried out at Al- Batool hospital in Mosul city, 150 cases of elective cesarean sections recruited in this study during the period from 1st December 2019 to the 1st June 2020 ,they divided to three groups according to route of antibiotic administration .The ratio of wound infections in group 1&2 was (5%) and 20% in group (3) patients who don’t received pre –operative prophylactic antibiotics 
. No significant differences in wound infection founded between group1&group2,whereas high rate of wound infection occurred in group3 p-value (0.014 ),in this study  single prophylactic doses of antibiotics give as much protection as multiple  doses in preventing post elective cesarean section wound infections . Obesity prior to pregnancy showed a statistically significant value as a cause of wound   infection   P-value   (0.001).   Analysis   of   the   results demonstrated    two    types    of    pathogens    were    identified Staphylococcus species (85%) and proteus (15%).