Demographic and Endoscopic Characteristics of Peptic Ulcer Disease in Mosul

Abstract

Background: Peptic ulcer disease (PUD) is a common gastrointestinal problem with significant morbidity and mortality despite introduction of effective therapy. Some aspects of this disease carry regional and ethnic variations. 
The  aim  of  the  present  study  is  to  demonstrate  demographic  and endoscopic  characteristics  of  gastroduodenal  ulcers  in  Mosul,  and display their frequencies and bleeding complications. 
Patients & methods :  This is a retrospective, cross-sectional study of 326 patients diagnosed endoscopically with peptic ulcers in Al-Salam General  Hospital  in  Mosul  during  a  period  from  January  2018  to December  2020.  Details  of  patients  records  regarding  demographic, clinical, and endoscopic findings were collected and analyzed. Results:  Total  number  of  patients  was  326.  Duodenal  ulcer  (DU) comprised 286 patients (205 males, 81 females), and gastric ulcer (GU) 40 (18 males, 22 females). Mean age of  DU patients was 34.1 ± 13.9 years, and GU 54.9±15.3 years. Male:female ratio was (223/103, 2.2:1). DU:GU ratio was (286:40, 7.2:1). The main site of DU was the duodenal bulb (283/286, 99%) and for GU the antrum and lesser curve (28/40, 70%). Around 90% of ulcers were single. Bleeding was a presenting symptom in 20% of patients, and in 32.3% were associated with the use of mainly non-steroidal anti-inflammatory drugs (NSAIDs). Conclusions:    In  Mosul  city  DU  affects  a  relatively  younger  ages compared to GU. DU was more predominant in males. DU:GU ratio was wide. Ulcers were mainly single and located in the duodenal bulb and antrum of the stomach.  Bleeding was a common presentation of PUD. NSAIDs contributed largely to bleeding complications.